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SCIENCERISE: PHARMACEUTICAL SCIENCE

Results of Analysis of Epidemological Indicators of Viral Hepatitis C in Regions of the World as Part of Activities to Improve Pharmaceutical Provision for Patients

viral hepatitis affects hundreds of millions of people worldwide, the most dangerous of which are hepatitis b and c. the aim of our study was to study the prevalence and incidence of hc in the world a...

Advanced Research for Physico-chemical Properties and Parameters of Toxicity Piperazinium 2-((5-(furan-2-YL)-4-phenyl-4H-1,2,4-triazol-3-YL)THIO)acetate

the achievements of modern domestic pharmacy clearly prove the prospects of searching for biologically active molecules among 1,2,4-triazole derivatives. the aim of our work was to predict the safest ...

Phytochemicals Profile and In-vitro Antidiabetic Potentials of Fractionated Extracts of Entada Africana and Leptadenia Hastata

aim: to confirm their use in the management of diabetes and to determine the numerous phytochemicals present that may be connected to the active performance of the plants, the fractionated extracts of...

Comparative Analysis of Drug Consumption for the Treatment of Epilepsy in Ukraine, Kazakhstan and Belarus

the aim to conduct a comparative analysis of the population's consumption of antiepileptic drugs in the retail pharmaceutical markets of developing countries, including ukraine, kazakhstan and belarus...

Development of A Unified Approach to the Method of Identification, Quantitative Determination of Active Substances and Accompanying Impurities in A Combined Drug by HPLC Method

the aim of the work is to develop a method of identification, quantification of acetylsalicylic and ascorbic acids in the combined presence and concomitant impurities in the combined drug in the form ...

Spectrophotometric Methods for Quantitative Determination of Sotalol in Tablets

the aim of the work. to develop a method for spectrophotometric determination of sotalol with diazonium salts. establish optimal conditions for the quantitative determination of sotalol in drugs. vali...

An Overview on 1,2,4-triazole and 1,3,4-thiadiazole Derivatives as Potential Anesthesic and Anti-inflammatory Agents

the aim. the purpose of this review is to summarize data on the synthesis and structural modification of heterocyclic systems with triazole and thiadiazole fragments in molecules as promising objects ...

Synthesis and Anticonvulsant Activity Evaluation of N-[(2,4-dichlorophenyl)methyl]-2-(2,4-dioxo-1h-quinazolin-3-yl)acetamide Novel 1-benzylsubstituted Derivatives

the aim. synthesis of 1-benzylsubstituted derivatives of n-[(2,4-dichlorophenyl)methyl]-2-(2,4-dioxo-1h-quinazolin-3-yl)acetamide, and determination of affinity to gabaergic biotargets with the follow...

Antioxidant and Anti-cytolytic Activity of Parsnip (Pastinaca Sativa L.) Herb Thick Extract in Conditions of Catecholamine Myocardiodystrophy in Rats

the aim: to study the antioxidant and anticytolytic activity of the parsnip herb thick extract (phte) in conditions of catecholamine myocardial dystrophy in rats. materials and methods. catecholamine ...

New, Simple and Express Determination of Lamotrigine in Tablets by Using Diazole Red 2J

epilepsy is considered one of the most common chronic neurological diseases among humans. lamotrigine is an effective new-generation anticonvulsant, which is widely introduced to the pharmaceutical ma...

Status and Analysis of Trends in the Metformin -Based Drug Development: Formation of the Logistic System of Scientific Research

the aim of the work is analysis of the current state and trends in the metformin-based drug development with the subsequent formation of the logistics system of scientific research. materials and meth...

The Influence of Non-steroidal Anti-inflammatory Drugs with Different Mechanisms of Action on the Course of Stress Reaction, the Functional State of Kidneys, Liver, and Heart on the Model of Acute General Cooling

inhibitors of the arachidonic acid cascade have significant potential as the agents for the prevention of severe cold injuries. the results of the previous studies have demonstrated the pronounced fri...

The Analgesic and Anti-inflammatory Effect of Lawsone Isolated From Lawsonia Inermis

 this study aimed to assess the analgesic and anti-inflammatory effects of lawsone isolated from henna leaves (lawsonia inermis).  methods: a total of 120 healthy adult mice (weighing about ...

Substituted Acyl Thioureas and Acyl Thiosemicarbazides: Synthesis and Biological Activity (Minireview)

acyl isothiocyanates and their functional derivatives (acyl thioureas and acyl thiosemicarbazides) are an important group of organic compounds that are widely used in the synthesis of heterocycles and...

Comprehensive Study for the Development of Rectal Suppositories with Diosmin and Hesperidin

the aim. to conduct a comprehensive study of biphasic-type suppositories that contain diosmin and hesperidin. materials and methods. samples of biphasic-type suppositories with a mass of 4.0 were obje...

Establishment of Quality Indicators of Promising Plant Raw Materials - Underground Organs of Rumex Confertus Willd

the aim is to study the morphological and anatomical structure of the underground organs of r. confertus and to establish the type of medicinal plant raw materials, to determine a number of its indica...

Research of the Causes and Consequences of Mobing in the Lablor Team of A Pharmacy Establishment

the aim of the article is to analyze the causes and consequences of mobbing, which occurs in the staff of the pharmacy. materials and methods. the methods used in the study include methods of theoreti...

Development of A Method for Determining the Morpholinium Thiazotate Using More Economic and Green GC/MS Assay with an Fid Detector

one of the main steps in the pharmaceutical development of drugs is the choice of quality control methods. the correctness of the method must be confirmed by validation. in addition, manufacturers tak...

The Management of Premenstrual Syndrome: Results of A Questionnaire Survey of Women in Lviv Pharmacies, Ukraine

the aim. to establish the prevalence of pms symptoms and evaluate the medication management of this disorder in lviv. materials and methods. the objects of the study were: scientific publications rela...

Research on the Use of Motivational Tools in the Practical Activity of Pharmaceutical Specialists

the aim. research on the peculiarities of the use of modern motivational tools by domestic employers in the pharmaceutical industry (including training and involvement of pharmaceutical specialists in...

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